Day Two (14th May 2025)Wednesday, 14 May 2025 - CET/CEST (Cent Europe Summer, GMT+2)

To drive down the cost of goods, biomanufacturers are striving towards maximizing facility utilization, increasing process efficiency, and maintaining a robust supply chain—all without compromising the quality of the final product.

Designed specifically for the hydration of powdered media, feeds, or buffers, the Oceo Rover single-use system delivers consistent solutions on demand in less than half the time of conventional processes. In this session, you will learn how to transform your bioprocessing operations with the first alternative system for media feed and buffer preparation. The Oceo Rover will be demonstrated together with chemically defined media from FUJFILM Irvine Scientific to help you achieve greater efficiencies.

Discover how the Oceo Rover:

• Delivers bioprocessing solutions for both process development and manufacturing, in the upstream and downstream environment, and across multiple modalities
• Hydrates and sterilizes media, feeds, or buffers as a single-unit operation
• Provides repeatable and scalable results using prepacked, single-use cartridges with our chemically defined media portfolio
• Improves environmental, health, and safety considerations and eliminates the risk of cross-contamination via a self-contained system
• Features access to world-class support to help you identify the ideal hydration protocol and optimize your workflows

Cell culture media are complex mixture that are critical to ensure the robust production of biopharmaceutical products. Cell culture media quality is however dependent of multiple parameters such as raw material quality and preparation process. While protocols are in place at the biopharmaceutical site as well as at the raw material manufacturer to ensure reproducible preparation, there is to date little technology available to verify that the composition of the medium produce is as expected. This gap lies within the fact that media composition is very heterogenous comprising compounds in very large ranges of concentrations from nM to M and very different chemical properties including metals, salts, organic compounds as well as polymers and proteins. This study shows how we can come closer to closing this gap with an on-line fluorescence-based method for the monitoring of cell culture media preparation. We will show the characterization of the method including sensitivity and scale up as well as the challenges we face for implementation in commercial facilities.