Thursday, September 24 - EST (Eastern Time, UTC-05:00
Exploring the application of transformer-based language models to mRNA design, demonstrating how AI can accelerate the optimization of codon sequences for improved vaccine and therapeutic performance.
- Sizhen Li - Computational Science Lead, Sanofi
Development of stabilized nanoparticle formulations designed to enable multiple routes of mRNA delivery beyond traditional intravenous administration, including inhaled, topical, and other localized delivery methods to expand therapeutic applications.
Engineering nanoparticle platforms with enhanced stability and tissue-specific targeting capabilities, allowing mRNA therapeutics to be delivered directly to disease sites through diverse administration routes while maintaining cargo integrity.
Development of tissue-specific lipid nanoparticle (LNP) formulations engineered to selectively deliver mRNA therapeutics to muscle tissue, bone marrow, and immune cells, utilizing targeted delivery strategies to enhance therapeutic efficacy and reduce systemic exposure
- From screening early-stage nucleic acid payloads up to GMP-scale production, researchers need tools that grow up with their workflow and keep the process consistent.
•Sunshine and Stunner AF team up to cover the critical steps in LNP development
•See how this duo helps you hit the ground running with your first gene therapy, reduces hands-on time, and delivers more meaningful sample
- Ben Knappett - Product Manager, Sunny Suite, Unchained Labs