Retatrutide: A Breakthrough Triagonist Uniting Molecular Design and Sustainable Manufacturing
Michael Kopach, PhD, Associate Vice President, Synthetic Molecule Design and Development, Eli Lilly and Company
#macromolecular therapeutics #peptides #peptide manufacturing #cmc strategies #peptide chemistry #large molecule therapeutics
Why this is critically important to the peptide / macromolecular therapeutics industry
Retatrutide is an example of a first-in-class triagonist with the potential to transform the treatment of obesity, type 2 diabetes, obstructive sleep apnea, and osteoarthritic knee pain. Beyond its pharmacology, the molecule incorporates both α- and non-coded amino acids, showcasing advanced molecular design in peptide therapeutics.
This session will delve into the learnings from the design and manufacturing of Retatrutide, allowing you to understand how they intersect to deliver impactful therapies.
Zooming in on the manufacturing process, Retatrutide highlights true innovation in peptide manufacturing and CMC strategies. Its development has led to a hybrid solid-phase/liquid-phase peptide synthesis (SPPS/LPPS) platform, setting new standards for efficiency, sustainability, and global scalability. How can we take it as a case study for the future of peptide chemistry, peptide manufacturing, and commercialization of therapeutics? Come along to the session to find out…
How will it help your career?
You’ll obtain insights in to the full cycle of peptide therapeutic development, from expert molecular design to successful commercial stage manufacturing. This is your chance to understand the integration of peptide chemistry and CMC strategies for complex molecules, develop strategies to drive efficiency, sustainability, and scalability successfully, and discover how to translate innovative molecular design into a tangible, clinically and commercially viable therapy. This session will help you derive strategies for the full cycle and lead you into your next stage of success.
Ideal for those working in peptide chemistry, peptide manufacturing, CMC, operational efficiency, and macromolecular therapeutics.
Don’t let this opportunity pass you by – discover how to position your work at the forefront of peptide innovation.
