Xuan ZhouSenior Scientist, Oligonucleotide Development at BiogenSpeaker
Profile
With over eight years of experience in oligonucleotide solid-phase and liquid-phase synthesis process development, Xuan Zhou is an accomplished scientist in antisense oligonucleotide (ASO) chemistry. Currently serving as Associate Director and ASO Process Chemistry Lead at Biogen, Xuan has pioneered advancements in oligonucleotide process development, including the successful creation of a scalable liquid-phase synthesis process. They have also published multiple patents and manuscripts contributing to the advancement of therapeutic oligonucleotide manufacturing.
Xuan joined Biogen in 2016 as Scientist I and has since progressed through roles of increasing responsibility, including Scientist II (2019-2022), Senior Scientist (2022-2024), and now ASO Process Chemistry Lead. In each role, Xuan has focused on developing innovative methods to enhance process efficiency and scalability in oligonucleotide synthesis.
Prior to joining Biogen, Xuan completed a Post-Doctoral Research Fellowship in Organic Chemistry at the University of Texas at Austin, following a Ph.D. in Medicinal Chemistry from Sichuan University in China.
Agenda Sessions
Preparation of Anti-Sense Oligonucleotide (ASO) via Hybrid Synthesis
, 2:30pmView Session