Agenda March 17, 2027: Main Conference Day One - PT (Pacific Time, GMT-08:00)
Upstream development sessions must move beyond simple productivity stories and focus on the real levers that improve robustness and reproducibility. This session will explore media optimization, feed strategy, metabolism control, and nutrient management approaches that translate across scales and stages. It should emphasize practical gains in process performance and quality.
This session will explore practical uses of AI, modeling, and automated analytics in process optimization, experimental design, monitoring, and process understanding. Talks should emphasize measurable value, not hype.
A major advisor pain point was the lag in getting actionable product-quality data back during development. This session will focus on PAT, at-line analytics, autosampling, soft sensors, and integrated monitoring strategies that bring product-quality insight closer to real time. This shall aloinclude feedback control strategies, optimally using multi input and multipel output controllers. It should also tackle the evolving definition of PAT in biologics manufacturing.
Scale-up readiness is often shaped as much by internal trust and burden of proof as by technical readiness. This session will examine scale-down models, pilot-scale decision frameworks, readiness assessments, and process packages that improve transferability and organizational confidence.
As pipelines diversify, upstream teams are rethinking how far standard platforms can stretch. This panel will explore where platform upstream still creates major speed and efficiency benefits, where it introduces hidden constraints, and how teams decide when to customize. It is a strong bridge between technical work and strategic portfolio decisions.