May 11-14, 2026
Hynes Convention CenterBoston, MAKey Sessions
Realizing the Promise of CRISPR Therapeutics
RaPID Display and Selection of Pseudo-natural Products
The Science Behind the GLP-1 Medicines: A Historic View and Future Outlook
Clinical Update on Oligonucleotides for Cardiovascular Disease
Antibody Oligonucleotide Conjugates (AOCs): RNA Delivery Beyond the Liver
“I Love Conjugates”: The GalNAc Revolution and Its Impact on Oligonucleotide Therapeutic Development
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Main Conference - Day 1 Keynote Sessions (May 20)
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Main Conference - Day 1 Keynote Sessions (May 20)
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6:30am - 7:30am
Registration
Breakfast Spotlight Presentations
Showing 3 of 3 Streams
Breakfast Spotlight Presentations 1
Breakfast Spotlight Presentations 2
Breakfast Spotlight Presentations 3
7:30am - 8:00am
Synthetic Peptide CMC Development and Experiences
Showing 1 of 1 Streams
Keynote and Plenary Session
8:10am - 8:15am
Chairperson’s Remarks: Keynote Day 1
8:15am - 9:00am
The Science Behind the GLP-1 Medicines: A Historic View and Future Outlook
9:00am - 9:45am
“I Love Conjugates”: The GalNAc Revolution and Its Impact on Oligonucleotide Therapeutic Development
9:45am - 10:15am
Networking Refreshment Break
Morning Keynote Session
Showing 1 of 1 Streams
Keynote and Plenary Session
10:15am - 11:00am
Realizing the Promise of CRISPR Therapeutics
11:00am - 11:45am
Oligonucleotide Therapeutics: Current Challenges and Opportunities
11:45am - 12:05pm
Transition to Spotlight Presentation/Panel Luncheons
Spotlight Presentation Luncheons
Showing 6 of 6 Streams
Spotlight Presentation Luncheon 1
Spotlight Presentation Luncheon 2
Spotlight Presentation Luncheon 3
Spotlight Presentation Luncheon 4
Spotlight Luncheon Presentation 5
Spotlight Presentation Luncheon 6
12:05pm - 12:35pm
Biodegradable Lipid Nanoparticles with Tunable Immunogenicity
The immunogenicity of ionizable lipids is a significant issue in applications such as gene editing or mRNA therapeutics. We have developed a novel chemical family of biodegradable lipids (COATSOME® SS Series) that exhibit exceptional stability in the circulating state and only break down when triggered by specific stimuli present in the cytosol. We will present further data on the cytokine profile, toxicity, and efficacy of COATSOME® SS Series in multiple animal models.
12:05pm - 12:35pm
Advancing RNA Vaccines and Therapeutics: Cutting-edge Innovations in mRNA Manufacturing
12:05pm - 12:35pm
Advancing Sustainability in the Oligonucleotides Industry: Strategies for Environmental Responsibility and Innovation
12:05pm - 12:35pm
Efficient Large-scale siRNA Manufacturing: Enzymatic Ligation of Short RNA Fragments
12:05pm - 12:35pm
Chromatographic Tools for the Bioanalysis of Oligonucleotide Therapeutics
12:35pm - 12:55pm
Short Networking Break
Afternoon Keynote Session
Showing 1 of 1 Streams
Keynote and Plenary Session
12:55pm - 1:00pm
Chairperson’s Remarks: Keynote Day 1
1:00pm - 1:45pm
Clinical Update on Oligonucleotides for Cardiovascular Disease
1:45pm - 2:30pm
Antibody Oligonucleotide Conjugates (AOCs): RNA Delivery Beyond the Liver
2:30pm - 3:30pm
Grand Opening of Poster and Exhibit Hall and Networking Refreshment Break
Showing 1 of 1 Streams
Keynote and Plenary Session
3:30pm - 4:15pm
RaPID Display and Selection of Pseudo-natural Products
This lecture discusses a new development of display format for the discovery of pseudo-natural products against intracellular targets of protein. The technology enables us to access unexplored chemical space with cell membrane permeability of macrocycles.
4:15pm - 5:00pm
Panel Discussion: Addressing the Challenges of Bringing New Therapeutic Modalities to Market: Technical and Regulatory Considerations
5:00pm - 6:30pm
Networking Reception in Poster and Exhibit Halls
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