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TIDES USA: Oligonucleotide & Peptide Therapeutics
May 11-14, 2026
Hynes Convention CenterBoston, MA

From Nanotechnology to Nucleic Acid Therapeutics: How Overcoming Skepticism and Barriers Led to New Cancer Treatments and Ways to Tackle a Global Health Challenge

Robert Langer, ScD, David H. Koch Institute Professor, Massachusetts Institute of Technology

#nanotechnology #nucleicacid #cancertreatments #macromolecules #oligonucleotidediscovery #drugdiscovery

Why this is critically important to the oligonucleotide / macromolecular therapeutics industry

The delivery of macromolecules, including nucleic acids, was once considered impossible. Today, we know this not to be true. In this keynote, Dr. Langer traces back to the field’s evolution all the way from 1974 to present day. Discussing the importance of how skepticism itself can be a barrier, he highlights the countless nucleic acid therapeutics available today, with many more in development – and what a grave error it would have been to fold to the skepticism of the past.

For those working in oligonucleotide discovery, macromolecular drug discovery, or therapeutic delivery, this session will recount the key strategies and breakthroughs that moved science forward to where we are now – overcoming translational barriers and the lessons learned that remain crucial today as the field continues to scale. You will discover how you can be at the forefront of change, help propel the industry into the next wave of discovery, and champion beliefs and tactics that will create tomorrow’s pioneering research.

How will it help your career?

You will obtain a unique historical and practical perspective on translating high-risk science into real-world therapies. Discover the lessons that will help you overcome barriers in the development and delivery of oligonucleotide and macromolecular therapeutics, link early-stage research to clinically impactful treatments, and adapt your mindset to be more strategic – anticipating challenges in scaling and complex therapies.

Ideal for those working in research and development, oligonucleotide chemistry, translational medicine, and drug delivery.

This is your opportunity to take away practical insights that can be applied to accelerate your projects, overcome hurdles and influence your organization’s therapeutic pipeline.

TIDES USA audience in session