Bioctogen is a Biotech CRO offering custom gene targeting services, featuring CRISPR-based EGE® technology, which increases knockin efficiency by 10-20-fold. Biocytogen also offers Immuno-Oncology drug validation services that rely on independently-developed humanized immune-checkpoint mouse models (e.g. B-hPD-1 mice) and immune-deficient, human immune system-reconstituted mice (B-NDG model). Our models can be used for antibody in vivo screening.