Key Sessions
Hanneke Schuitemaker, PhD
Vaccine Design for Potent and Durable Protective Immunity
Janssen Vaccines & Prevention B.V.
Hans de Haard, PhD
Efgartigimod: A Novel FcRn Antagonist in the Treatment of Autoimmune Diseases
Argenx
Carolyn Bertozzi, PhD
Therapeutic Opportunities in Glycoscience
Stanford University
Douglas Lauffenburger, PhD
Computational Systems Analysis of Host Immune Functions in Pathogen Infections and Vaccines
Massachusetts Institute of Technology
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MAIN CONFERENCE DEC.5 - PST/PDT (Pacific Daylight, GMT-7)
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MAIN CONFERENCE DEC.5 - PST/PDT (Pacific Daylight, GMT-7)
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7:15am - 8:15am60 mins
Registration and Breakfast
8:15am - 8:20am5 mins
Keynote Presentations- San Diego Ballroom AB
Chairwoman’s Welcome and Opening Remarks
- Janine Schuurman, Ph.D. - Vice President, Research, Genmab
8:20am - 9:00am40 mins
Keynote Presentations- San Diego Ballroom AB
Vaccine Design for Potent and Durable Protective Immunity
- Hanneke Schuitemaker, PhD - Global Head of Viral Vaccine Discovery and Translational Medicine, Janssen Vaccines & Prevention B.V.
9:00am - 9:05am5 mins
Keynote Presentations- San Diego Ballroom AB
Keynote Questions
9:05am - 9:45am40 mins
Keynote Presentations- San Diego Ballroom AB
Efgartigimod: A Novel FcRn Antagonist in the Treatment of Autoimmune Diseases
- Hans de Haard, PhD - Chief Scientific Officer, Argenx
9:45am - 9:50am5 mins
Keynote Presentations- San Diego Ballroom AB
Keynote Questions
9:50am - 10:30am40 mins
Keynote Presentations- San Diego Ballroom AB
Networking Refreshment Break
10:30am - 11:15am45 mins
Keynote Presentations- San Diego Ballroom AB
Therapeutic Opportunities in Glycoscience
- Carolyn Bertozzi, PhD - Baker Family Director, Stanford ChEM-H and Anne T. and Robert M. Bass Professor of Chemistry, Stanford University
11:15am - 11:55am40 mins
Keynote Presentations- San Diego Ballroom AB
Computational Systems Analysis of Host Immune Functions in Pathogen Infections and Vaccines
- Douglas Lauffenburger, PhD - Ford Professor of Bioengineering, Massachusetts Institute of Technology
11:55am - 12:00pm5 mins
Keynote Presentations- San Diego Ballroom AB
Keynote Questions
12:00pm - 12:15pm15 mins
Keynote Presentations- San Diego Ballroom AB
Transition to Scientific Luncheon Briefings
12:15pm - 1:15pm60 mins
Scientific Luncheon Briefing 1- Pacific Ballroom 14/15/18
From Lead Discovery through Optimization and Validation: A Case Study in Rapid Antibody Discovery
- Jean-Philippe Bürckert, Ph.D. - Director, Bioinformatics, Large Molecule Discovery, Charles River Laboratories
- Kalyani Mondal, Ph.D. - Associate Director, Biosensors, Charles River Laboratories
12:15pm - 1:15pm60 mins
Scientific Luncheon Briefing 2- Pacific Ballroom 16/17/19
Building Better Protein Therapeutics Using Machine Learning and Synthetic Biology
- Claes Gustafsson - Co-founder and Chief Commercial Officer, Atum Bio
12:15pm - 1:15pm60 mins
Scientific Luncheon Briefing 3- Pacific Ballroom 16
Fit-for-Purpose Platforms for Enhanced Therapeutic Antibody Discovery: Flexibility, Diversity, and Risk-Mitigation
- Jane Seagal, PhD - VP of Antibody Discovery, AlivaMab Discovery Services
12:15pm - 1:15pm60 mins
Scientific Luncheon Briefing 4- Pacific Ballroom 17
Writing the Future of Biologics with Synthetic DNA and Machine Learning
- Aaron Sato, PhD - Chief Scientific Officer, Twist Bioscience
12:15pm - 1:15pm60 mins
Scientific Luncheon Briefing 5- San Diego Ballroom AB
Ultralong CDR H3 Antibodies from Cows: Unique Genetics, Structural Biology, and Engineering Opportunities
- Vaughn Smider, M.D., Ph.D. - President, Applied Biomedical Science Institute
1:15pm - 1:45pm30 mins
Scientific Briefing 1- Pacific Ballroom 14
Coordinating Screening and Engineering Throughput for Antibody Discovery
- Colby Souders PhD - Senior Director of R&D, Abveris, A Division of Twist Bioscience
1:15pm - 1:45pm30 mins
Scientific Briefing 2- Pacific Ballroom 15
High-throughput and Automated Antibody Discovery at the Institute for Protein Innovation
- Roushu Zhang, PhD - Scientist, Institute for Protein Innovation
1:15pm - 1:45pm30 mins
Scientific Briefing 3- Pacific Ballroom 16
Streamlining Antibody Discovery with the Dotmatics Biology Solution
- Melanie Nelson, PhD - Senior Solutions Architect, Dotmatics
1:15pm - 1:45pm30 mins
Scientific Briefing 4- Pacific Ballroom 17
Better Data, Faster: High-Throughput Assays for Bispecific Antibody Evaluation
- Allan Atkinson - Field Application Scientist Manager, PerkinElmer
- Henry Qazi, PhD - Senior Product Specialist, PerkinElmer
1:15pm - 1:45pm30 mins
Scientific Briefing 5- San Diego Ballroom AB
Streamlining Antibody Discovery with the NaturalAntibody Machine Learning Solution
- Konrad Krawczyk, PhD - Chief Scientific Officer, NaturalAntibody
1:45pm - 2:15pm30 mins
Scientific Briefing 1- Pacific Ballroom 14
Single Source of Antibody Discovery and Protein Engineering Platform Accelerates Biologics Innovation
- George Wang, PhD - Vice President of Discovery and Preclinical Services, WuXi Biologics
1:45pm - 2:15pm30 mins
Scientific Briefing 2- Pacific Ballroom 15
Structure-Based Charge Calculations for Predicting Properties and Profiling Antibody Therapeutics
- Nels Thorsteinson - Director of Biologics, Chemical Computing Group
1:45pm - 2:15pm30 mins
Scientific Briefing 3- Pacific Ballroom 16
Integrated Data Analysis for Antibody Discovery
- Piotr van Rijssel - Application Specialist, ENPICOM
1:45pm - 2:15pm30 mins
Scientific Briefing 4- Pacific Ballroom 17
Process Development and Detailed Analytical Characterization of PicobodiesTM: a Novel Antibody Format Produced using Pelican Expression TechnologyTM
- Jeff Allen, Ph.D. - Vice President, Protein Sciences, Pelican Expression Technology
1:45pm - 2:15pm30 mins
Scientific Briefing 5- San Diego Ballroom AB
Human Single Domain Antibody Library Platform for Efficient Cell Therapy and Bispecific Discovery
- Jason Lajoie, PhD - Associate Director, Head of Lead Optimization, Alloy Therapeutics
2:25pm - 2:30pm5 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Chairman’s Remarks
- Karl Dane Wittrup, Ph.D. - C.P. Dubbs Professor, Massachusetts Institute of Technology
2:25pm - 2:30pm5 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
Co-Chairs’ Remarks
- Jean-Philippe Bürckert, Ph.D. - Director, Bioinformatics, Large Molecule Discovery, Charles River Laboratories
2:30pm - 3:00pm30 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Engineering Evolvability and Developability in Synthetic Ligand Scaffolds
- Benjamin Hackel, Ph.D. - Professor, University of Minnesota
2:30pm - 3:00pm30 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
Mining Large Antibody Sequence Datasets for Therapeutic Antibody Discovery
- Justin Barton - Principal Machine Learning Scientist, Alchemab Therapeutics
3:00pm - 3:30pm30 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Mini Proteins RaPIDly Generated by LassoGraft Technology
- Hiroaki Suga, Ph.D. - Professor of Chemistry, School of Science, University of Tokyo, Japan
3:00pm - 3:30pm30 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
Benchmarking Machine Learning Approaches for Antibody Specificity Prediction
- Victor Greiff, Ph.D. - Associate Professor for Computational and Systems Immunology, The University of Oslo
3:30pm - 4:00pm30 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Mini-protein Assisted Nuclear Delivery of Protein Therapeutics
- Xizi Zhang - Ph.D. Candidate, UC Berkeley
3:30pm - 4:00pm30 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
In Silico Antibody Optimization Enabled by Quantitative Predictions of Affinity and Naturalness of Sequence Variants by Artificial Intelligence
- Joshua Meier - Lead AI Scientist, Absci
4:00pm - 4:45pm45 mins
Networking Refreshment Break and Opening of Exhibit and Poster Hall
4:45pm - 5:15pm30 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Engineering Cyclic Peptides Using Yeast and mRNA Display
- Balaji Rao, PhD - Professor, Chemical and Biomolecular Engineering, North Carolina State University
4:45pm - 5:15pm30 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
Designing Clinical Antibodies with New Capabilities: Conditional Agonist/Antagonists, Logic Gates and Functional Switches
- Yanay Ofran, Ph.D. - Chief Executive Officer, Biolojic Design
5:15pm - 5:45pm30 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Epitope-Specific Antibody Design via Deep Learning-Based Structural Modeling
- Possu Huang, PhD - Assistant Professor of Bioengineering, Stanford University
5:15pm - 5:45pm30 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
Exploring Antibody Design Space Using Deep Neural Networks
- Sai Pooja Mahajan, PhD - Postdoctoral Fellow, The Johns Hopkins University
5:45pm - 6:15pm30 mins
Track 1: Miniprotein Engineering- San Diego Ballroom AB
Engineering of Novel Nanobody Scaffolds with Reduced Kidney Retention
- Lucinda Hall - Ph.D. Candidate, University of Alabama at Birmingham
5:45pm - 6:15pm30 mins
Track 2: Progress and Challenges of Computational Approaches for Antibody Discovery and Engineering- San Diego Ballroom C
Machine Derived Digital Signatures of Antibody Sequences Show Promise in Antibody Selection
- Brett Averso - Chief Technology Officer, EVQLV
6:15pm - 7:45pm90 mins
Opening Night Networking Reception, Exhibits and Poster Viewing
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