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Antibody Engineering & Therapeutics US
December 14 - 17, 2025
Marriott Marquis San Diego
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Main Conference Day 2 - PT (Pacific Time, GMT-08:00)

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Main Conference Day 2 - PT (Pacific Time, GMT-08:00)
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Showing 1 of 1 Streams
9:50am - 10:05am
Affinity by Design – Building Scientific Software Inspired by Natural Antibody Evolution
  • Romelia Salomon Ferrer - Global Head of Computational Drug Design, AQBioSim, Sandbox AQ
Showing 1 of 1 Streams
1:20pm - 1:30pm
Amazon Technology Showcase
  • Kemal Sonmez, PhD - Senior Applied AI Scientist, Amazon
1:30pm - 1:40pm
KinExA in the Era of AI and Biologics Innovation
  • Madelynn Grier, PhD - Staff Scientist, Sapidyne Instruments
2:00pm - 2:20pm
Ailux: Using AI to drive biologics innovation
  • Kyle Klaassen - Senior Director of Business Development, Ailux
Showing 1 of 1 Streams
4:25pm - 4:45pm
Beyond the Bench: High-Throughput Antibody Production with Built-in Scalability, Security, and AI-Ready Data
  • Lindsay Dawson - Staff Product Manager, Twist Bioscience
Showing 1 of 1 Streams
4:45pm - 5:15pm
Discovery of Next-Generation Brain Shuttles: Biodistribution Engineering through Multiplexed In Vivo Screening and AI-Guided Protein Design

TfR1 shuttles show promise for CNS therapeutics, but toxicities remain limiting. We introduce a high-throughput in vivo screening method to engineer novel brain shuttles. Powered by AI and Manifold's protein barcoding technology, our approach reveals novel shuttle targets and shuttles with enhanced tissue selectivity, reduced toxicity profiles, and optimized biodistribution.

  • Karen Duffy, PhD - Principal Scientist, Manifold Bio
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