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Main Conference Day 3 - PT (Pacific Time, GMT-08:00)
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Main Conference Day 3 - PT (Pacific Time, GMT-08:00)
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Track 1: Beyond Classic ADCs: Novel Payloads, Modalities & Mechanisms
2:15pm - 2:45pm
Expanding the Toolbox: Non-natural Amino Acids Enable Development of a CD30 Dual-payload ADC
- Megan Rice - Associate Principal Scientist, AstraZeneca
Showing 1 of 1 Streams
Track 2: Engineering Innovative Functionality into Antibody Domains
4:15pm - 4:45pm
Expanding the Fc Functional Spectrum: A Diverse Repertoire of Novel Fc Variants for Enhanced Potency, Complete Effector Silencing, Extended Persistence, and Accelerated Pathogenic IgG Clearance
Our group has developed a portfolio of novel Fc variants comprising distinct designs for enhanced target-cell clearance, complete silencing of Fc-mediated effector functions, extended serum persistence, and accelerated elimination of pathogenic IgG autoantibodies. Their marked functional gains relative to established Fc variants incorporated into marketed therapeutics will be presented.
- Sang Taek Jung, PhD - Associate Professor, Seoul National University
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