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Main Conference Day 3 - PT (Pacific Time, GMT-08:00)
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Main Conference Day 3 - PT (Pacific Time, GMT-08:00)
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Track 2: Engineering Antibody Interfaces: Unlocking New Biology
8:45am - 9:15am
From Nanobody Repertoires to Programmable Medicines: Proteomics, AF3-TurboAb, and Multivalent Design
This talk will present an integrated nanobody engineering platform spanning serum proteomics, AF3-TurboAb–enabled antibody-antigen modeling, and multivalent biologic design. I will highlight how scalable structural prediction and interface analysis guide programmable nanobody therapeutics for infectious disease, toxin neutralization, and cancer precision medicine.
- Yi Shi, Ph.D. - Professor, University of Pittsburgh, School of Medicine
Showing 1 of 1 Streams
Track 1: Beyond Classic ADCs: Novel Payloads, Modalities & Mechanisms
3:15pm - 3:45pm
DLL3 Antibody-Based Radiotheranostics: From ImmunoPET to Targeted Radioligand Therapy
This presentation will highlight the development of DLL3-targeted antibody-based radiotheranostic agents, spanning immunoPET imaging and targeted radioligand therapy. Preclinical and early clinical studies demonstrate the potential of DLL3 as a platform for patient selection, treatment monitoring, and precision radionuclide therapy across neuroendocrine malignancies.
- Salomon Tendler, MD, PhD - Assistant Attending Physician, Memorial Sloan Kettering Cancer Center
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