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Antibody Engineering & Therapeutics US
December 15 - 18, 2024
Marriott Marquis San DiegoLive In-Person Event: December 15 - 18, 2024

Sara Colombetti, PhD
Global Head of Oncology Discovery Pharmacology at Roche Innovation Center Zürich


In 2004 I received my Ph.D. in Molecular and Cellular biology at the San Raffaele Scientific Institute in Milan (Italy). After a post-doc in cancer immunotherapy at the Ludwig Institute for Cancer Research (Lausanne branch) and later at Cytos Biotechnology (Zurich) I have joined the Roche Innovation Center Zurich (RICZ) in 2009, where I initially led the In Vivo Models team and then the Immuno-Pharmacodynamics and PK Unit. In 2018 I have been appointed Global Head of Oncology Discovery Pharmacology, a global group with teams in Switzerland, Germany and France. The group is part of the Oncology Discovery Unit within the Roche pharma Research and Development (pRED) division. The focus of the group is the development of cutting edge preclinical models for the evaluation of all pRED Oncology portfolio assets.

Agenda Sessions

  • Workshop Co-Moderator’s Remarks

  • Humanized Mouse Models as Key Preclinical Tools to Develop Glofitamab, A Next Generation T cell Engager for the Treatment of Hematological Malignancies