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BIO-Europe
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November 6–8, 2023Munich, Germany

Navigo Proteins

Profile

Navigo Proteins is a premier protein engineering company, discovering, and developing Precision Affinity Ligands. Our Precision Affinity Ligands are based on small, stable, and highly engineerable single-chain scaffold proteins. These are functionalized in two different applications:

1. Targeted next-gen therapeutics based on novel Affilin® target binders (PRECISION TARGETING)

2. Custom affinity purification of biologics (PRECISION CAPTURING®) 


1. Precision Targeting - Affilin® Biopharmaceuticals

 Unparalleled flexibility to design next-generation Affilin®-based biopharmaceuticals: (ADC, radio conjugates, bispecifics, CAR-T ligands and targeted exosome therapy). 

  • Affilin® ligand Discovery – Selection/Screening to identify novel binders for target of interest. 
  • Ready-to-Partner Affilin® ligands against validated tumor and I/O targets (HER2, PSMA, EGFR, PD-L1 and more) 
  • In-house development of targeted therapeutics (e.g., Affilin® Radiotheranostics and Affilin® bispecifics)


2. Precision Capturing® - Marketed Products: 

For antibody purification: 

-Praesto Jetted A 50 (using a Navigo NGL Impact® A ligand) for ultra-high binding mAb purification

-coming in 2021 – NGL Impact® A Hi pH for purification of pH sensitive mAbs and Fc-fusions

For recombinant proteins: 

-NGL COVID-19 Spike Protein Affinity Resin for purification of protein-based SARS-Cov-2 vaccines